Essential Bioinformatics for Global LeadersⅠto begin on October 4, 2017

 Class List of Fall Semester 2017

“Essential Bioinformatics for Global LeadersⅠ” will begin on October 4. This is a class for students in “Minor Course of Science and Technology for Global Leaders”. But all master’s & doctoral students can take it if you have interest. The class will be conducted in English.

Theme & Objective

Prof. GouraudBioinformatics is an interdisciplinary research area at the interface between biological science and computational science, the ultimate goal of which is to better understand living cells and their functioning at the molecular level. It involves the technologies that use computers for the storage, retrieval, manipulation, understanding and distribution of information related to biological macromolecules such as DNA, RNA, protein, and even more.
The “Essential Bioinformatics for Global Leaders I” classes has been conceived for non-biologist as well as biologist students wishing to acquire global leader skills and enrich their scientific English. This first series of interactive classes, given in friendly English, will provide the students with the fundamental cellular and molecular biology knowledge needed to understand bioinformatics. Important notions of bioinformatics, its logical background and its cutting-edge applications in basic biology research, biotechnology and biomedical sciences will also be introduced. The classes include lectures, discussion and practices [wet lab (basic molecular biology experiments) and dry lab (databases exploration, data analysis using software)]. The students do not need to understand the mathematical details in the field.

Message to Students

These interactive classes are open to everyone, from biological background or not. They will provide you with the basis for a general understanding of cell and molecular biology. If you are new to Biological Sciences, you will have a chance to do your first biological experiments. If you already know about the field, it will be a great opportunity for you to improve your skills, widen your knowledge and in any cases listen and practice your English! Do not hesitate to join that fun experience!

Lecture Outline

Subject
Essential Bioinformatics for Global LeadersⅠ [17S1003
Number of Credits
2.0
Instructor
Gouraud, Sabine (Project Associate Professor of Ochanomizu University)
Target Audience
Graduate Students
Date, Time and Location
October 4, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408
October 11, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408
October 18, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408
October 25, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408
November 1, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408
November 8, 5-8 (13:20-16:30) Science building 1 R521, Science building 2 R202
November 15, 5-8 (13:20-16:30) Science building 2 R202
November 22, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408
November 29, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408
December 6, 5-8 (13:20-16:30) Science building 1 R521
December 13, 5-8 (13:20-16:30) Science building 1 R521
Lecture Plan

1) Oct 4th, 2017: 90 min, Graduate School of Humanities room 408
Introduction to the “Essential Bioinformatics for Global Leader I” classes and general bioinformatics concept [style: lecture, discussion]
-Program of the classes, expectation of students
-History, general definition/overview of bioinformatics and its applications in different fields of science.

2) Oct 11th, 2017: 90 min, Graduate School of Humanities room 408
Basics of molecular biology I [style: lecture, discussion]
Introduction to the cell, organization and composition, cells in their context (models of cells, cancer, infection, development, tissue renewal…)

3) Oct 18st, 2017: 90 min, Graduate School of Humanities room 408
Basics of molecular biology II [style: lecture, discussion, computer practice]
PROTEIN, structure/function, analytical techniques and tools, proteomics databases exploration

4) Oct 25st, 2017: 90 min, Graduate School of Humanities room 408
Basics of molecular biology III [style: lecture, discussion]
DNA, structure, basic genetic mechanisms (RNA, replication, protein translation, mutation, gene repair…)

5) Nov 1th, 2017: 90 min, Graduate School of Humanities room 408
Basics of molecular biology IV [style: lecture, discussion, computer practice]
Gene expression analytical techniques and tools, genomics databases exploration, application and social implication of biological investigation.

6-7) Nov 8th, 2017: 180 min, Science building 1, Practice Room 521+ Science building 2 room 202
RNA isolation [style: wet lab]
RNA extraction from animal tissue/cells (Guanidinium thiocyanate-phenol-chloroform method), RNA quantitation assessment (Nanodrop)

8-9) Nov 15th, 2017: 180 min, Science building 2 room 202
RNA quality assessment (Bioanalyzer) + RT-qPCR experiment [style: wet lab]

10) Nov 22th, 2017: 90 min, Graduate School of Humanities room 408
Gene expression analysis I: [style: computer practice, discussion]
RT-qPCR data analysis

11) Nov 29th, 2017: 90 min, Graduate School of Humanities room 408
Gene expression analysis II: [style: computer practice, discussion]
Introduction to a larger scale gene expression analysis technique (ex. PCR array)

12-13) Dec 6th, 2017: 180 min, Science building 1, Practice room 521
Protein expression analysis I [style: wet lab]
Protein extraction from animal tissue/cells, protein quantitation, protein separation by acrylamide gel electrophoresis (western-blotting)

14-15) Dec 13th, 2017: 180 min, Science building 1, Practice room 521
Protein expression analysis II [style: wet lab, computer practice, discussion]
Semi-quantitative western-blotting (immunoblotting, Image J data analysis)
Conclusion/discussion

Textbook/Reference
Essential Cell Biology (Garland Science), Molecular Biology of the Cell(Garland Science), Bioinfomratics for Beginners (Academic Press) Supratim Choudhuri

Registration

Registration Period: Mon., October 2 through Sat., October 14
If you cannot register during above period, please contact Academic Affairs Office in Student Affairs Building.

Contact

Ochanomizu University Leading Graduate School Promotion Center
Tel: 03-5978-5775
E-mail: